These two monographs attempt to list all "proven and established results" bearing on their titles. The presentation is systematic and detailed, befits a handbook, and is compressed into 56 pages on echoviruses (about 400 references) and 23 pages on reoviruses (about 250 references). Each monograph treats history, classification and nomenclature, virion structure, effects of chemical and physical agents, antigenic character, interaction with man and and other mammals, and epidemiology. For the echovirus group the spectrum of disease includes meningitis, encephalitis, rash, gastrointestinal tract infection, and respiratory manifestations. For the reoviruses, serologic evidence of infection is so common that no syndromes can be assigned with certainty.
The clinician may chance on a provocative item (eg, that reoviruses can withstand formaldehyde for one hour), but most of this carefully compiled information is directed at the laboratory virologist and epidemiologist. The echovirus section is current through November 1965 with an addendum into