Serotonin! Here, indeed is a substance to conjure with. At least its myriad physiologic and pathologic associations have conjured up thousands of papers, while inspiring clinicians and researchers and even a bit of poesy:
This man was addicted to moanin',
Confusion, edema and groanin',
Great tricolored blushes,
And died from too much serotonin.
—W. B. Bean and D. Funk
Archives of Internal Medicine103:189 (Feb) 1959
"Serotonin," the word as a book title might discourage the general reader and attract the connoisseur. Both would be wrong. The biochemically-oriented, expecting (justifiably) a veritable Handbuch, would do better to consult Page's comprehensive discussions (1945 and 1958) in Physiological Reviews. Others will find a pleasant evening's overview of this metabolic jack-ofmany-trades, which has "replaced epinephrine as a sure road to tenure for the pharmacologist", by the man who (with Rapport and Green) first isolated serotonin twenty years ago. A formidable