We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

PPD Antigens and the Diagnosis of Mycobacterial Diseases A Study of Atypical Mycobacterial Disease in Oklahoma

Lance Fogan, MD, MPH
Arch Intern Med. 1969;124(1):49-54. doi:10.1001/archinte.1969.00300170051009.
Text Size: A A A
Published online


Atypical mycobacteria were isolated from 240 of the 3,211 persons in Oklahoma's tuberculosis (TB) register. Fifty-one of the patients excreting atypical mycobacteria had disease caused by these organisms. Nonchromogens were the organisms in 26 (51%), photochromogens in 20 (39%), and scotochromogens in 5 (10%). A battery of mycobacterial purified protein derivative antigens (PPD-S, -Y, -G, -B, and -F) was applied to 34 patients with atypical mycobacterial disease, and to 34 patients with tuberculosis. Reactions to more than one antigen were observed in 30 (88%) of the former, and in 33 (97%) of the latter group. The largest reaction corresponded to the homologous antigen in 14 of 20 patients with nonchromogen organisms, 6 of 11 with photochromogen organisms, 1 of 3 with scotochromogen organisms, and in 28 of 34 patients with TB. Skin test reactions verified the laboratory diagnosis in the majority of cases. Multiple uniform-sized reactions were common however, and


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.