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ARTICLE |

Carcinoid and Serotonin Recent Results in Cancer Research, vol 15.

Erik Ask-Upmark, MD
Arch Intern Med. 1969;123(6):733. doi:10.1001/archinte.1969.00300160123029.
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ABSTRACT

The author of the present volume is the distinguished director of the Southern Bio-Research Institute and the A. P. Cooke Memorial Cancer Laboratory of Lakeland, Fla. His book deals with the metabolite, 5-hydroxytryptamine, also known as enteramine or serotonin, particularly with regard to its connection with carcinoid tumors.

Carcinoids were baptized in 1907 by Oberndorfer. Cassidy described the clinical syndrome in 1931 which carries his name. See for example the chapter on the heart in Tratado de Alergia, Editorial Cientifico Medica, (1960). The substance responsible for the syndrome was identified by Erspamer in 1952.

Repeated observations have been published since; these are reviewed, but there are some omissions. It fails to include the important work done in Spain, as well as any reference to the familial occurrence of such tumors (first observed by myself and published in 1960).

The clinician may be somewhat distracted by repeated references to results of

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