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Sudden Death in Infancy.

Jay M. Arena, MD
Arch Intern Med. 1968;122(4):378. doi:10.1001/archinte.1968.00300090088025.
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This is a 103-page monograph of a ten-year study of "Sudden Unexpected Death in Infancy" (SUD or Cot Death) occurring in Copenhagen, a city of 1,348,000 people in the northern part of the temperate zone. The relationship of SUD to total infant mortality, artificial feeding, age (2 to 4 months), seasonal variation of births and deaths (predominately in winter), simultaneous twin deaths (rare), and typical case histories are discussed. Legal autopsies were performed on 164 infants during a six-year period (1957 to 1963) at the University Institute of Forensic Medicine with complete histological examination of all organs along with extensive bacteriological and virological studies. On the basis of these examinations three separate and distinct groups were found. Group 1 was comprised of 43 infants in whom the cause of death was established convincingly. In group 2 (41 infants), minor pathological changes (predominantly slight respiratory infection) were found that were not


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