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Deep Thrombophlebitis: Pathophysiology and Treatment.

Herbert L. Fred, MD
Arch Intern Med. 1968;122(1):90. doi:10.1001/archinte.1968.00300060092036.
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"The general purpose of this monograph is to bring into more realistic focus the acute and chronic problems of inflammation and thrombosis in the veins; its specific objective is to correlate the pathophysiology with altered hemodynamics in acute thrombophlebitis and in the postphlebitic limb." Doctor Haller accomplishes these aims admirably. He provides an interesting discussion of the historical development of the subject along with a detailed but concise description of the clinical, diagnostic, and therapeutic aspects of deep thrombophlebitis. His material is well organized and timely. Particularly informative are his chapters on the pathophysiology of extensive deep thrombophlebitis and the serious complications of deep thrombophlebitis and their treatment. He argues convincingly for prompt medical and aggressive surgical management of deep thrombophlebitis, and with certain exceptions, presents his views carefully and clearly, supporting them with numerous, well-chosen references. Other advantages of this monograph are brevity, large print, high quality paper, and


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