This sixth edition of this splendid reference text serves to confirm Dr. Walter Modell's prefatory remarks: "It is a volume of expert opinion designed to provide the American physician with a comprehensive source of clear, concise, authoritative, and practical answers to the continually recurring question of which drug in a rapidly changing scene, is at the critical moment, the drug of choice for an actual therapeutic problem." In pursuit of this lofty purpose, he succeeds most admirably.
Forty-six distinguished clinicians and pharmacologists have contributed 41 chapters. Discussions are crisp, penetrating, and comprehensive—obviously written by experts who enjoy a working-investigative familiarity with the therapeutic agents they describe. The organization of sections varies with individual essayists, but clarity and rational advice are hallmarks. There is no nonsense here; efficacy and toxicity are discussed with refreshing candor, a characteristic that has come to epitomize the works of Modell.
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