0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Calcified Annulus Fibrosus With Mitral Insufficiency in the Marfan Syndrome

Marvin Grossman, MC, USN; A. Paul Knott Jr., MC, USNR; William J. Jacoby Jr., MC, USN
Arch Intern Med. 1968;121(6):561-563. doi:10.1001/archinte.1968.03640060075014.
Text Size: A A A
Published online

The impetus to investigation of cardiovascular complications in the Marfan syndrome was the descriptions of aortic dilatation and dissecting aneurysm1,2 in 1943. A number of necropsy series3-8 subsequently published showed increased frequency of cardiovascular lesions. These reports focused their attention on the aortic pathology (dissecting aneurysm, fusiform aneurysm, and dilated aortic ring), with little emphasis placed on other vascular abnormalities. Thickening, wrinkling, nodularity, shortened chordae tendineae, and other deformities of the mitral valve were alluded to as incidental findings.

Recent reports9-15 have stressed the increased frequency with which significant mitral insufficiency is being recognized in the Marfan syndrome. However, association of this valvular defect with a calcified mitral annulus has been infrequent.6,15

We report a patient with the Marfan syndrome who had mitral insufficiency and massive calcification of the annulus fibrosus.

Patient Summary  This 21-year-old white woman was referred to the Naval Hospital, Great Lakes, 111,

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();