This volume is a collection of reviews primarily by surgeons from New York and Minnesota dedicated to Dr. Owen H. Wangensteen, their teacher. Dr. Irving M. Ariel has edited these into a readable and coordinated form that provides a current review for the physician interested in cancer. This type of volume is not too helpful for the average practitioner but provides a current reference source for the hospital library.
Dr. Harris Busch, from the Department of Pharmacology at Baylor University, provides a worthwhile chapter on the molecular biology of cancer. The discussion on blood flow to tumors is a study with radioactive microspheres where in 14 human carcinomas the postinjection concentration of normal to tumor tissue varied from 2.5:1 up to 30:1. If it is true that chemotherapeutic drugs are not specific but randomly effect any cell in deoxyribonucleic acid synthesis, then this information on poor blood supply in cancer
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