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Advances in Immunogenetics.

Robert H. Moser, MC, USA
Arch Intern Med. 1968;121(4):375. doi:10.1001/archinte.1968.03640040069016.
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This is a penetrating discussion of the emerging science of immunogenetics. As hematologist Greenwalt states in his prefatory remarks, "One of the major goals (of the book) was to expose to a general audience the increasing maze of polymorphisms being described in the blood of man and animals, with allusion to practical clinical applications where existent". The text is divided into seven chapters; six are contributed by other writers including hematologists, pediatricians, a geneticist, and a biologist.

The neophyte is introduced into nomenclature, methodology, and classification of immunoglobulins in chapter 1 and is carried forward in easy steps through pathologic variations of immunoglobulins, genetic modulations, phenotypic variations of haptoglobins, transferrin and red cell enzymes, and erythrocyte grouping. A concluding chapter discusses type specific antigens in the animal kingdom.

It is comprehensive and absorbing; illustrations are generous and appropriate. In certain areas the nomenclature will be "tough sledding" for those less


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