Fulminating Disseminated Aspergillosis Complicating Peritoneal Dialysis in Eclampsia

D. A. Ross, MB; D. C. Anderson, MB, MRCP; M. C. Macnaughton, MB, FRCOG; W. K. Stewart, MB, MRCP
Arch Intern Med. 1968;121(2):183-188. doi:10.1001/archinte.1968.03640020071015.
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Disseminated aspergillosis was not reported before the advent of antibiotics. In a review of the world literature Tan et al1 found 22 cases occurring since 1939, and described a further one. Almost all these cases, and others reported subsequently2,3 had received antibiotics or steroids, or both, and most had an underlying debilitating illness; one patient had Cushing's syndrome.4

The present case is unusual in that the portal of entry seems to have been a peritoneal infection resulting from peritoneal dialysis.

Patient Summary  A primigravida, age 22, had a normal antenatal course, until Nov 8, 1965 (36th week), when her blood pressure (BP) was 130/80 mm Hg and the urine contained a trace of protein. The major clinical events, together with antibiotic, steroid, and dialysis treatment are summarized in Fig 1. On Nov 20 (38th week) at 4:30 pm nausea, vomiting, and intermittent epigastric pain developed. The pain


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