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ARTICLE |

Genetic Relationships in Familial Leukemia and Lymphoma

Perry G. Rigby, MD; Peyton T. Pratt, MD; Robert C. Rosenlof, MD; Henry M. Lemon, MD
Arch Intern Med. 1968;121(1):67-70. doi:10.1001/archinte.1968.03640010069011.
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Thirty-nine multiple family cases have been recorded with 77 pairs and 91 involved relatives having leukemia or lymphoma. Thirty-two of the 39 families involved a close genetic relationship between affected siblings or parent-child pairs. The multiple family case members died earlier than single family case members on a comparative study. This suggests that genetic factors are of importance in the etiology of these malignant hematologic proliferations.

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