We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Hypokalemia and Electrocardiographic Abnormalities During Acute Alcohol Withdrawal

William R. Vetter, MD; Lawrence H. Cohn, MD; Michel Reichgott, MD
Arch Intern Med. 1967;120(5):536-541. doi:10.1001/archinte.1967.00300040020003.
Text Size: A A A
Published online


THE SYNDROMES of acute alcohol withdrawal have been well defined,1 but despite a large number of patients, relatively little is known of the metabolic changes accompanying withdrawal. Abnormalities in electrolyte metabolism during this acute phase have been reported,2-4 but few prospective studies have been carried out. However, it has been reported that no significant alteration occurs in the serum electrolytes of normal volunteers during recovery from ingestion of large quantities of alcohol5,6; in addition, no abnormalities were observed in a small series of chronic alcoholic patients.7

During observation and evaluation of chronic alcoholic patients undergoing withdrawal at San Francisco General Hospital it was noted that the levels of serum potassium were frequently low and that cardiac arrhythmias and alterations in the ST segment, T, and U waves in the electrocardiograms were common. Consequently, a study was undertaken to determine the frequency and severity of hypokalemia


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.