This book is a well-written, liberally illustrated monograph on one of medicine's most interesting pathophysiological entities. Dr. Sackner entitles the book Scleroderma, although it is divided into chapters each of which describes one of the multisystem manifestations of the disease. Therefore, "Progressive Systemic Scleroses" might have been a more appropriate appellation to prepare the reader for his thorough stepwise discussion.
The author presents his own extensive experience with this disease, comprising a series of 65 cases. In addition, he reviews the literature which includes 516 references. This is basically a descriptive presentation which reflects the current paucity of knowledge concerning the pathophysiology of scleroderma. It is pertinent to note that Dr. Sackner devotes only two paragraphs of this long monograph to treatment, illustrating the frustration encountered when one attempts to help patients with this disease.
There are occasional printing errors. On page 122, "acute fibrinous pericarditis was associated with uremia