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ARTICLE |

Unusual Manifestations of Rhabdomyosarcoma

A. JERALD ROTHENBERG, MD; CLIFFORD G. PILZ, MD
Arch Intern Med. 1966;118(5):446-448. doi:10.1001/archinte.1966.00290170034006.
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RHABDOMYOSARCOMAS are considered to be rare tumors. Accurate statistics of the incidence of these tumors are not available but a review of the literature reveals that only 230 cases have been reported since 1937. This type of neoplasm was first described by C. O. Weber in 1854, in the tongue of a 21-year-old man.1 The first comprehensive report on tumors of myogenic origin was made by Teevan in 1863 2 and in 1900 Genevet introduced the term rhabdomyoma for all tumors derived from striated muscle.3 The first large series of rhabdomyosarcomas was reported by Rakov in 1937.4

Subsequently, different forms of rhabdomyosarcomas were recognized and their natural history described. In 1958 Enterline and Horn described a distinctive form of the tumor and called it an alveolar rhabdomyosarcoma.5 At this time the embryonal form of rhabdomyosarcoma also began to be recognized. None of the reported tumors, regardless of cellular classification, have

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