One of the many satisfactions in the practice of internal medicine is the accurate diagnosis of a rare disorder. The presence of an unusual disease often provides the inquisitive physician with a unique opportunity to probe nature's various pathways of action. In 1657, William Harvey so beautifully expressed the need to investigate the unusual afflictions of man.
Nature is nowhere accustomed more openly to display her secret mysteries than in cases where she shows traces of her workings apart from the beaten path; nor is there any better way to advance the proper practice of medicine than to give our minds to the discovery of the usual law of nature by careful investigation of cases or rarer forms of disease. For it has been found in almost all things that Nature is hardly perceived unless we are deprived of them or they become deranged in some way.
Dr. Neuton S.