RECENT advances in the science and practice of medicine have resulted in a marked reduction in the morbidity and mortality from naturally occurring diseases affecting man. At the same time, modern standards of medical care have created an ever-increasing and diversified group of artificially induced diseases. These have been referred to as iatrogenic disorders or "diseases of medical progress." The importance of these disorders is attested to by the recent space and time given to them in at least two books written on the subject,1,2 a portion of a medical periodical regularly devoted to them,3 and in several symposia on this theme.4 Concern at the national level regarding one aspect of this broad problem is reflected in the Registry of Adverse Reactions recently formed by the American Medical Association Council on Drugs and by a similar program inaugurated by the Food and Drug Administration.
The disseminated or