0
ARTICLE |

Sodium Ampicillin Given Parenterally

MARVIN TURCK, MD; RONALD H. SMITH, MD; JAMES F. WALLACE, MD; ROBERT G. PETERSDORF, MD
Arch Intern Med. 1966;117(2):242-249. doi:10.1001/archinte.1966.03870080086013.
Text Size: A A A
Published online

AMPICILLIN, is a semisynthetic penicillin which is effective against penicillinsusceptible gram-positive organisms as well as many prevalent gram-negative pathogens.1-7 The oral preparation in clinical use which consists of the free acid of ampicillin has been under extensive trial since 1961 and was made available commercially in the United States in 1964. Several studies have indicated that it is fairly stable in the presence of gastric acid, and is absorbed readily from the gastrointestinal tract; is not bound to protein in appreciable quantity; is distributed well into most tissues; and generally is well tolerated and safe.8-10 Less is known regarding the sodium salt of ampicillin which recently has been made available for parenteral administration.11-14 This report describes the use of the sodium salt of ampicillin in the treatment of 124 hospitalized patients with a variety of systemic infections.

Materials and Methods 

Selection of Patients.  —Patients admitted to the General Medical and

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();