Introduction A PRIMARY reduction in the physically dissolved fraction of carbon dioxide in blood defines the state of primary respiratory alkalosis (primary hypocapnia). The quantity of physically dissolved CO2 ([H2CO3]) in blood depends on the partial pressure of CO2 (Pco2).1Arterial blood Pco2, is in equilibrium with pulmonary alveolar air Pco2, which in turn is directly proportional to alveolar air CO2 concentration (F CO2).Increase in alveolar ventilation, which defines the state of hyperventilation, results in reduction of alveolar F CO2 and therefore reduction in alveolar and arterial Pco2. A schematic demonstration of F CO2-Pco2 relationship is seen in Fig 1. Thus, primary hyperventilation results in a reduction in alveolar Pco2 and consequential reduction in arterial Pco2-the state of respiratory alkalosis.
Hyperventilation. —The term "hyperventilation" should not be used to describe an accelerated rate of respiration (tachypnea), since such does not necessarily result in an increase in alveolar ventilation. Furthermore,
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Purchase Online Access to this article for 24 hours
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
Instructions
Thank you for submitting a comment on this article. It will be reviewed by JAMA Internal Medicine editors. You will be notified when your comment has been published. Comments should not exceed 500 words of text and 10 references.
Do not submit personal medical questions or information that could identify a specific patient, questions about a particular case, or general inquiries to an author. Only content that has not been published, posted, or submitted elsewhere should be submitted. By submitting this Comment, you and any coauthors transfer copyright to the journal if your Comment is posted.
* = Required Field
Disclosure of Any Conflicts of Interest* Indicate all relevant conflicts of interest of each author below, including all relevant financial interests, activities, and relationships within the past 3 years including, but not limited to, employment, affiliation, grants or funding, consultancies, honoraria or payment, speakers’ bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued. If all authors have none, check "No potential conflicts or relevant financial interests" in the box below. Please also indicate any funding received in support of this work. The information will be posted with your response.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 32
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
and access these and other features:
Register Now
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Need assistance?
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.