My reaction to this book is one of malaise. Most of it is pretty good and it certainly seems to be encyclopedic. But for all this value there is about it an air of injudiciousness. It is written in a strident style, in some parts smacking of the Sunday supplements, and the italics have been layed on with a broad brush. The author emphatically advocates the use of anticoagulants and his arguments in their favor seem overdrawn, employing every shred of evidence however dubious and cataloging every case report however uncontrolled. His opinions and his practices based upon them may turn out to be the best possible, but his manner of advancing them arouses skepticism.