The Annual Review of Pharmacology has already arrived. It now needs no introductory data—all volumes published are uniformly of high caliber.
Chauncey Leake's "Review of Reviews" chapter should be pointed out, and especially his mention of two recent developments in pharmacology which he calls fads, namely, molecular pharmacology and clinical pharmacology. Whether these will prove to have been fads or not is less important than the periodic need for self-examination and examination of one's work. Does a variant serve the purpose of a discipline or is it selfserving, or does it merely serve publishers who are eager to bring out new journals? There is a continuous question of equilibrium, broadly applicable, and each one will answer the question to himself according to his own conscience.
There are 23 other chapters in this informative review volume. Timely and outstanding chapters are "Genetic Factors in Relation to Drugs" by Kalow, "Behavioral Pharmacology"