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Article |

The Thymus in Immunobiology—Structure, Function, and Role in Disease.

Hugh Fudenberg, MD
Arch Intern Med. 1965;116(2):310-311. doi:10.1001/archinte.1965.03870020150033.
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This comprehensive volume is composed of the 36 papers presented at the Thymus Conference in Minneapolis in 1962 and represents a highly successful effort to collect and collate all relevant information on the structure and function of the thymus and other central lymphatic tissue (bursa of Fabricius and other gut-associated lymphoid tissue) in normal and abnormal states. The anatomy of the thymus (both by the light and by the electron microscope) is presented in authoritative papers by Smith and by Clark, the chemistry by Szent-Gyorgyi et al, and the embryology by Auerbach. An incisive review by Fisher analyzes thymus pathology in various human disease states. The major portion of the volume is devoted to studies of the kinetics, dynamics, and fates of thymus cell populations and the effect of thymectomy and/or bursectomy on these parameters and on the immune response. Every active worker in the field is represented.

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