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Clinical Chemistry: Principles and Procedures.

Rex D. Couch, MD
Arch Intern Med. 1965;115(3):370-371. doi:10.1001/archinte.1965.03860150114035.
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Clinical Chemistry is a burgeoning science, bristling with manifold instruments, a profusion of technique, and a multitude of new ideas toward methodology, quality control, and the question of what is "normal." Only a few short years ago we were told that the primary tool of the clinical pathologist of the future would be a voltmeter. This stage of the "future" (and we seem to reach the future in increasingly shorter eras nowadays) is already in the past. Nearly gone too, are the days when an author could present to this voluminous discipline a sound, unpretentious, simplified, and basic introduction.

Clinical Chemistry probably sits at the far side of a milestone of publications on the subject. In a recent survey 1 of nearly 1,000 clinical laboratories, the impact of automation was clearly demonstrated, a number of tests already being automated in more than 40% of responding laboratories. This was probably the


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