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Balloon Radioautography in Differentiation of Benign and Malignant Gastric Lesions

Arch Intern Med. 1965;115(3):326-329. doi:10.1001/archinte.1965.03860150070013.
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I. Introduction  THAT various malignant tumors can selectively concentrate phosphorus (utilizing radioactive 32P as a label) has been well documented by many authors.1-4 In general, in vivo evaluation of 32P concentration in neoplastic lesions had been limited to readily accessible tumors which could be counted directly with Geiger-Müller probes. Nakayama 4 did explore in vivo counting of esophageal and gastric neoplasms with considerable success.In 1960, Ackerman and his associates 5 described a new radioautographic technique to permit in vivo detection of gastric neoplasms. After the intravenous administration of 32P, a rubber balloon coated with a photosensitive emulsion is introduced into the stomach. The degree of darkening of the photosensitive surface of the balloon is a measure of the degree of radioactivity of the stomach.The accuracy of balloon radioautography in the differentiation of benign and malignant gastric lesions in comparison with the accuracy of exfoliative


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