Genetics and Metabolism.

John M. Opitz, MD
Arch Intern Med. 1964;114(5):718. doi:10.1001/archinte.1964.03860110188040.
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This book is highly recommended to anyone in biology and medicine who would like to read a coherent and broad treatment of the biochemistry of heredity and the genetics of biochemistry. The scope of this book is slightly different from that of Sager and Ryan,1 and it is more up to date. In its 673 pages it covers a great variety of subjects organized in 14 chapters, including cell structure and function, genetic systems, mutation, kinetics and dynamics of metabolism, mutation and the agents of metabolic control, metabolic patterns, genetic units of structure and function, gene interaction and balance, environmental modification of phenotype, the continuity of cellular organization, gene action and development, plant pigments, and finally biochemical genetics in humans. The breadth of coverage is its great virtue, for in no book is so much diverse factual knowledge brought together; but it is also one of its failings, for it


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