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ARTICLE |

Enzymes in Blood Plasma.

Edward E. Mason, MD
Arch Intern Med. 1964;114(1):169-170. doi:10.1001/archinte.1964.03860070215043.
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ABSTRACT

This monograph reviews some 589 papers published mostly during the decade from 1951 to 1961 inclusive with regard to the possible clinical significance of plasma enzymes. It appears that plasma enzymes are either the result of cell secretion such as acid and alkaline phosphatase, amylase, pepsin, and a few others or they are lost from cells undergoing sudden disintegration or reversible increase in permeability.

The recent decade has added little to our knowledge and ability to use the secreted enzymes. The bulk of recent literature deals with plasma enzymes which leak out of cells and probably have no specific purpose in plasma. Much search has been made for organ specific and disease specific plasma enzymes or combinations of enzymes. In general the plasma enzyme levels are of greatest use in situations where the site of enzyme loss is either established by other diagnostic information or at least highly suspect. It

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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