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Pulmonary Infarct Secondary to Dirofilaria Larvae

Arch Intern Med. 1964;113(5):702-705. doi:10.1001/archinte.1964.00280110082016.
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Dirofilaria is the generic name for long filiform nematodes that commonly infect dogs and other mammals. In Dirofilaria immitis infection, the adult parasite lodges in the right ventricular cavity and/or the pulmonary arteries and gives rise to circulating microfilaria. Despite its frequency in domesticated dogs, D immitis infection is rare, and subcutaneous or orbital infections by other species of Dirofilaria are uncommon. Faust1 reviewed the literature in 1957 and found only 37 cases of human infection; only three were D immitis (heart worm) infection. All of the other cases involved orbital or subcutaneous tissues and were classified as D conjunctivae or D repens infections. Other instances of subcutaneous infection have been reported by Sams and Beck,2 Jung and Harris,3 and Lenth.4 Dashiele 5 reported the first instance of human pulmonary involvement by recognizing larval dirofilariae in branches of the pulmonary artery within a "coin lesion." We


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