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Cardiac Arrhythmias in Sarcoidosis

ANTHONY W. NISSEN, MD; JOHN B. BERTE, MD
Arch Intern Med. 1964;113(2):275-282. doi:10.1001/archinte.1964.00280080111020.
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Since myocardial sarcoidosis was described in 1929,1 there have been reported to date some 35 cases in which death was due directly to this manifestation of the disease.2,3 In over 50% of these cases death was sudden, and often the existence of myocardial lesions had not been suspected clinically.

Because of the paucity of antemortem case studies in the literature, and because of the significant clinical incidence of cardiac abnormalities in sarcoidosis, it was felt warranted to publish our experiences with cardiac arrhythmias in five patients with sarcoidosis. While two of these patients are still living, and hence the diagnosis of myocardial sarcoidosis remains tentative, it was felt that their inclusion might be useful in indicating the course and treatment of this disease.

Report of Cases 

Case 1.  —The patient was a 21-year-old Negro woman admitted Nov 29, 1961, with complaints of chest pain, cough, and shortness of

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