Hashimoto's Disease (Struma Lymphomatosa) in Identical Twins

Arch Intern Med. 1964;113(1):70-71. doi:10.1001/archinte.1964.00280070072013.
Text Size: A A A
Published online

Accumulating evidence indicates that Hashimoto's disease (struma lymphomatosa) is a hereditary disorder with thyroid autoantibodies (Witebsky 1 and Roitt2). This is shown by a number of family studies. Dunning 3 reported three cases in one family. Hall et al 4 demonstrated "circulating autoantibodies in 22 out of 39 siblings of patients with autoimmune thyroid disease," and De-Groot et al5 found autoantibodies in low titers in five out of seven members of a family with this disease. When Irvine et al6 described the condition in two sets of identical twins, it gave further proof of the hereditary nature of the condition. We are reporting the third set of identical twins.

Report of Cases  A 22-year-old white female, one of identical twins, (case 1) was admitted to Mercy Hospital Nov 13, 1961, for an enlarged thyroid of seven months' duration.Both parents and three brothers were alive and well.


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 18

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.