With the accelerating increase in the volume and sophistication of researches in the basic sciences having to do with clinical surgery, there is a need to periodically assess the correctness of our traditional concepts, such as those of wound repair, resistance to infection, and organ physiology. The introductory chapters of textbooks of surgery which deal with basic principles frequently remain unchanged through successive editions of the same textbook, failing to make the alterations in basic concepts dictated by the results of researches done during the interval since the previous edition. One purpose of this volume is to assess the present status of some of these fundamental concepts. To a degree this objective is reached.
The volume consists of six review articles. In the first, the current concept of the mechanism of inflammation is discussed with reference to recent investigations. There is a carefully documented methodical discussion by Ehrlich, who has