To a casual reader, unfamiliar with the subject, this book will appear like a crazy quilt of quaintly empirical, unrelated items that have varying degrees of significance. Corneal transplantation is described in animals and man, but not thoroughly enough to be of much help or interest to an eye surgeon. The principles and techniques of plastic and of blood vessel surgery are described, but plastic or vascular surgeons will be distressed by the omission of much essential information. Immunologists or protein chemists may find reasons to be disappointed with the chapters that consider transplantation from their particular point of view. Some recent advances at the periphery of the subject are not covered by references to existing comprehensive reviews but rather by a list of authors most in the public eye. What could be the reason for an acknowledged leader in the field to come forth with this type of book?