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Maffucci's Syndrome

Arch Intern Med. 1962;109(2):186-191. doi:10.1001/archinte.1962.03620140058009.
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At the time of this writing 43 cases of Maffucci's syndrome of dyschondroplasia, multiple cavernous venous hemangiomata, and phlebectasia have been reported. The most comprehensive reviews of the subject are by Carleton and Bean.1,2 For the most part, prior descriptions have emphasized the skeletal deformities, the angiomata, and the increased incidence of malignancies, particularly sarcomata. Sometimes also the phlebectasia has been marked and deforming. This patient is unique in the severity of his venous changes and in the resultant circulatory deficit.

Report of Case  The patient is a 22-year-old white male American seaman, who was admitted in 1960 for consideration of vein surgery to his lower extremities. He stated that he was the product of a normal pregnancy but that at birth some asymmetry of his limbs was observed which has been present since. To his knowledge he has always had large irregular blotchy purplish areas of his arms


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