We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

New Diuretics and Antihypertensive Agents

Mark L. Armstrong, M.D.
Arch Intern Med. 1961;108(1):164. doi:10.1001/archinte.1961.03620070166022.
Text Size: A A A
Published online


The drugs covered in this volume are restricted to those which have appeared within the past four years: the benzothiadiazine, phthalimidine, and spirolactone diuretics, and the antihypertensive agents guanethidine, bretylium, and inhibitors of mononamine oxidase and dopa-decarboxylation.

The specific investigations reported are introduced by six review articles to provide appropriate context. Thus Grollman summarizes the most widely held views of the mechanisms of urine formation and diuretic action; Kirkendall reviews concepts of the mechanisms involved in hypertension, and Imbriglia reviews the pathology of hypertension. In addition, Rennick presents a lucid account of the pharmacodynamics of the new diuretics, based largely on animal studies. Parallel articles for the antihypertensive drugs are presented by Sjoerdsma on monoamine oxidase inhibitors and α-methyl dopa and by Brodie and Kuntzman on agents selectively depleting catechol amines.

Most of the information contained in this volume has been replicated in numerous publications. Bound together as a series


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.