New books are received with varying degrees of excitement and expectation of a clarification of knowledge and the possibility of new horizons. The subject here comprises the basis of the universe of living things, their function, malfunction, interrelations, and susceptibility to manipulation; the whole of biological basic science and clinical medicine approached from the micromolecularphysicochemical viewpoint. In subject it is not unrelated to another symposium on the "Regulation of Cell Metabolism" edited by Wolstenholme and O'Connor, which was received at the same time and which would appeal more to the laboratory worker. Greenberg and Harper are biochemists at the University of California Medical Center in San Francisco. They have organized their symposium to include 13 physicians and 13 philosophers. Each contributor is a specialist who was asked to bring thoughts from his field of knowledge which would be of most interest to students of enzymes in health and disease. The
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