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Arteriosclerosis:  Presbyosclerosis, Atherosclerosis, Arteriolosclerosis

Julius Bauer, M.D.
Arch Intern Med. 1960;106(3):313-315. doi:10.1001/archinte.1960.03820030001001.
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Not infrequently, a clinical teacher has to answer the questions of both undergraduate and postgraduate students on how to diagnose arteriosclerosis and how to evaluate its significance as to prognosis and management. The following is my answer.

Arteriosclerosis—literally, hardening of the arteries—comprises several different pathologic processes, each of different clinical significance. One type is due to senescence, that is, to the physiologic process of aging. This type is best designated as presbyosclerosis and concerns chiefly the vascular media. Another is caused by a metabolic disorder and consequent disease of the intima; this is known as atherosclerosis. A third type consists of a proliferative process in the smallest peripheral arteries (arterioles); it was first described in 1872 by Gull and Sutton as "arterio-capillary fibrosis" and is now called arteriolosclerosis. I do not intend to discuss this third type here, as it most commonly represents the structural consequence of a long-standing systolic

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