The Pharmacology and Clinical Use of Diuretics. By Carroll A. Handley, Ph.D., and John H. Moyer, M.D. Price, $6. Pp. 194, with 79 illustrations. Charles C Thomas, Publisher, 301-327 E. Lawrence Ave., Springfield, 111., 1959.
"The Physiological Basis of Diuretic Therapy" is one of the best books concerned with the action of diuretic agents to come to my attention. Dr. Pitts' approach to the problem is a basic one, and he goes into detail concerning what is known about renal physiology and the pharmacology of these compounds. In an excellent introductory section he considers body fluid volumes, the composition of body fluids and abnormalities found in edema, and the mechanisms of homeostasis. This section is well written and mentions all currently popular concepts in these fields. It alone is worth the price of the book. The second part of the volume is devoted to a detailed discussion of the mechanism