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Needle Biopsy of the Liver

AMARJIT SINGH, M.D., M.R.C.P.; S. S. JOLLY, M.D.; SURRINDER SINGH, M.B.
AMA Arch Intern Med. 1960;105(3):424-430. doi:10.1001/archinte.1960.00270150078008.
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Two decades have elapsed since Iverson and Roholm 1 popularized liver biopsy as a diagnostic procedure. Ever since, numerous series of papers have been published from different countries emphasizing the importance and efficacy of this procedure as a diagnostic and research method.2-4 Its importance in conditions which affect the liver parenchyma diffusely, namely, hepatitis, fatty liver, amyloidosis, etc., is already established. More recently, however, the postmortem sampling technique adopted by Braunstein 5 has further established the accuracy of liver biopsy in the diagnosis and estimation of degree of cirrhosis of the liver.

The incidence of various liver diseases depends upon the nutritional standards of a country, being highest in Asia and Africa. It is therefore likely that certain differences may be expected from the pattern of various liver diseases described from outside Asia. With this object in view the following observations have been collected.

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