This ninth edition of Clark's text continues the standards of brevity set by previous editions. The size of the volume reflects the variety of agents which must be considered and not the author's verbosity. Indeed, in many sections the lack of detail leads to statements that are true only in a limited way. "Pethidine has no appreciable depressant action on the cough center in man and, although it has some depressant action on the respiratory center, it does not depress the respiration of the newborn infant in doses which produce analgesia during labour" (p. 304). While such statements might be misleading to the unguided reader, they should not be a handicap to the use of this volume as the text for an introductory course in pharmacology.
The text is well printed and illustrated and deserves special credit for the excellence of the chemical formulas. It is a particular pleasure to