0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Discussion of Direct Relief of Coronary Occlusion:  The Anatomic Pathologic Problem

HERRMAN L. BLUMGART, M.D.; PAUL M. ZOLL, M.D.; GEORGE S. KURLAND, M.D.
AMA Arch Intern Med. 1959;104(6):862-869. doi:10.1001/archinte.1959.00270120018004.
Text Size: A A A
Published online

The Central Problem  The therapeutic problem in coronary artery disease is created by the existence of structural coronary narrowing or complete occlusion causing diminished coronary blood flow. The reestablishment of a satisfactory blood supply then becomes the central objecttive.

The Nature of the Occlusion  Excluding the more unusual causes, such as embolism, syphilitic narrowing of the coronary ostia, necrotizing arteritis, or calcific aortic stenosis impinging on the ostia, one deals with coronary atherosclerosis as the causative process in more than 90% of patients with angina pectoris or acute myocardial infarction. An effective therapeutic approach must be based on knowledge of the anatomic changes and of the pathologic physiology of the atherosclerotic process.

The Anatomic Characteristics of Coronary Atherosclerosis.  —The obstructing atherosclerotic lesions are arterial, not venous, and reside in the main stems and primary branches. They are almost entirely epicardial. The highest incidence of occlusions is not directly at the

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 19

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();