This volume contains the papers and the discussions following their presentation at the Ciba Colloquium on "The Nature and Actions of the Internal Secretions of the Pancreas," in London, June 21-23, 1955. The seventeen essays deal with a wide range of subject within the central theme, and one cannot choose among them for excellence.
The first two papers discuss the destruction of the α-cells by a chemical agent and the metabolic effects of their loss from the organism. The following discussions are concerned with the relationship of growth hormone and blood insulin activity and the control of the secretory activity of both the α- and the β-cells. This is considered from the standpoint of nervous control, metabolic factors, and endocrine influence in each case. In this same vein, the effects of hypophysectomy and prolonged STH administration on the α-cells are presented.
The next several papers are concerned with the chemical