This book is the verbatim account of a three-day session, sponsored by The Josiah Macy, Jr. Foundation, to which were invited twenty-five clinicians and scientists in widely diverse fields. The common denominators were that each of the participants had some interest in the function of the brain and each was well known in his respective field. These fields ranged widely from neuroanatomy, biochemistry, psychology, and physiology to clinical and experimental psychiatry.
The sessions were mainly devoted to consideration of the psychosomimetic drugs and their relationship to schizophrenia. Five topics were presented by individual investigators, heavily interspersed with the comments, questions, and reflections of the other participants. The first paper covered the general field of lysergic acid diethylamide (LSD-25) and related compounds. The second topic dealt with the effects of various drugs on the behavior of both experimental animals and human beings. The third and fourth presentations were mainly related to