This is the record of two successive symposia held in London, the first a well-attended meeting sponsored by the two learned societies and the second a small conference at Ciba Foundation House. There is therefore some inequality of style and some unavoidable overlap in the record. Thus, the last section of the societies' meeting dealt with the "origin and significance of histamine in the body" and the first section of the Ciba symposium with the "origin and fate of histamine in the body." Still, repetition is the mother of studies and is no more than a minor defect in a volume which uncovers some of the broad vistas of the known and unknown properties of this nearly ubiquitious substance.
Those who read for general information will discover many interesting aspects of the problem, such as the large difference between endogenous and exogenous histamine, the probability that histamine exists intracellularly in