The foreword for the present volume, the forty-sixth of a series, states that the material was selected with the interests of the general practitioner, the general surgeon, and the diagnostician in mind. From 629 papers published between Dec. 1, 1953, and Nov. 30, 1954, 63 are republished in lull, 52 by abridgement, 20 by abstract, and 495 by title. This material is directed toward a broad audience certainly, for, as stated, "to present adequately the work of the Mayo Clinic and the Mayo Foundation" representative material of the specialties and the basic sciences is included. Subject material is presented under the broad headings of alimentary tract; genitourinary tract; ductless glands; blood and circulating organs; dermatology; head, trunk, and extremities; thorax; brain, spinal cord, and nerves; radiology; physical medicine and rehabilitation; anesthesia, gas, and intravenous therapy, and miscellaneous. Under Miscellaneous, discussions of subjects from antibiotics to photomicrography appear. The papers are