There are certain aspects of this very long treatise which will meet with general approval. It is one, however, which will satisfy neither the psychiatrically oriented internist nor the psychiatrist who is at the same time a good doctor. In the corpus of the book there is a remarkable failure to separate demonstrated fact from belief. This is particularly true where many pharmacologic agents, analeptics, vitamins, and so forth are recommended wholeheartedly for the treatment of various conditions. Evidence of any controlled study to illuminate this therapeutic jungle land is lacking. There is great need for a book to clarify the frequently beclouded central terrain which exists between psychiatry and general medicine. This book, keeping close to the orthodox views of the past, fails to satisfy the need.