This is the first of a series of short papers on treatment of various disorders of particular interest to internists. The authors chosen for this series are entitled because of original investigations and special study to speak with some authority on the subjects which they discuss. They were asked by the Editorial Board to present their own ideas of the most acceptable plans for treatment of the condition under discussion rather than a comprehensive review of the literature. In almost every instance, however, the bibliographies accompanying the articles contain references to the recent important contributions on the subject. While there will at times be variations in opinions and emphasis from those expressed by other authorities in the given field, the Editors feel sure that each article will serve as a reliable and useful guide for the practicing physician. The series is presented to our readers with confidence and enthusiasm. P.