This book is an extension and elaboration of the material presented by Dameshek and Ester in "The Spleen and Hypersplenism" (1948). Like the earlier volume, this one consists of a series of graphic outlines of the chart-type format used by the authors in their presentation of the American Medical Association exhibit on this subject. Consequently, the material is presented in outline form rather than in the style of a fully documented monograph or text.
The authors briefly review the anatomy, histology, and physiology of the spleen, including in the latter a consideration of possible relationships of the spleen and bone marrow to the endocrine system. Hypersplenism is defined next, and the mechanisms of splenic hyperactivity are presented in brief outline form and followed by a series of presentations of data describing cases of splenic neutropenia, thrombocytopenia, anemia, and pancytopenia. In each case the authors present the data and their interpretation