This is another of the series of books including the papers of the University of Minnesota symposia on topics of current medical interest. The participants include most of the outstanding workers in rheumatic fever in the United States at this time. There are 23 papers in which original contributions on all phases of the rheumatic fever problem are presented. The present concept of widespread connective tissue damage following invasion of the body by type A hemolytic streptococci is abundantly supported by these researches. Dr. George Murphy adduces evidence for extensive damage to heart muscle fibers early in rheumatic fever and thinks Aschoff bodies often arise from these damaged myofibers rather than from damaged interstitial collagen.
New concepts of the way in which rheumatic lesions result from Streptococcus infection are brought forward by Lewis Thomas and Chandler Stetson.
In several reports on the treatment of rheumatic fever it is agreed that