There has been a need for a book of this title and scope for a considerable time. The enormous expansion of drug therapeutics within the past few years has resulted in a situation in which the physician finds himself employing drugs more than half of which were not known ten years ago. The consequence and penalty of this is a marked increase in the incidence of toxic reactions to drugs. The present book is valuable in being a fairly comprehensive cataloguing of the reactions reported in the current literature, but its telegraphic style and the lack of judicial discrimination in presenting a survey of the problems involved detract much from its usefulness. There are a few errors and some oversights which may prove disturbing. For example, the drug mephenesin is listed on page 42 with attendant reactions and the drug "myanesin" on page 51 with a slightly different set of
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