0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

EFFECTS IN RHEUMATOID ARTHRITIS OF HYDROCORTISONE AND CORTISONE INJECTED INTRA-ARTICULARLY

MORRIS ZIFF, Ph.D, M.D.; EDWARD SCULL, M.D.; DENYS FORD, M.D.; CURRIER McEWEN, M.D.; JOSEPH J. BUNIM, M.D.
AMA Arch Intern Med. 1952;90(6):774-784. doi:10.1001/archinte.1952.00240120049005.
Text Size: A A A
Published online

THE LOCAL action of cortisone1 has been well demonstrated in the treatment of diseases of the eye.2 Freyberg and co-workers3 injected cortisone intraarticularly in eight patients with rheumatoid arthritis and observed temporary improvement in several. Hollander and associates4 described the use of both cortisone and hydrocortisone locally in a group of patients with rheumatoid arthritis and other diseases. On the basis of clinical response and the change in intra-articular temperature on the day following injection of the hormone, they concluded that hydrocortisone was effective in suppressing inflammation and that cortisone was inactive in this respect.

In the present report are given the results obtained by serial intra-articular injections of cortisone and hydrocortisone in nine patients with rheumatoid arthritis and one patient with rheumatoid spondylitis with peripheral joint involvement. Seven of the patients had bilateral effusions in the knees, so that it was possible to obtain control observations between cortisone and

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 91

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();