The term antibiotic is defined in this book as a substance derived from living organisms and capable of adversely modifying the vital functions of specific organisms. The book is not a treatise on antibiosis, but a dictionary or encyclopedia. It provides in alphabetical order authoritative information on a great many substances with antibiotic activity. The source of the substance is named, the method of extraction, the chemical and physical properties, and, when available, the spectrum, structural formula, toxicological, pharmacological, and clinical properties. A very complete bibilography is included.
The principal author, Dr. Leonard Karel, is Executive Secretary of the Pharmacologic Section, Division of Research Grants, in the National Institutes of Health, United States Public Health Service. Mrs. Roach is his assistant.
The volume ought to be of very considerable usefulness to the specialist in pharmacology.